Review on the development of simple paper-based and thread-based devices for chemistry classrooms
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Abstract
This article gathered research articles involving development of simple paper- and thread-based analytical devices for chemistry classrooms allowing students to visualize and learn easily. This type of analytical devices has been developed as an alternative analytical method to high cost of conventional liquid-based instrumental analysis. Currently, researchers have been developing simple paper- and thread-based devices for variety of analyses, for examples, determination of chemical reaction rate, colorimetric analysis, health diagnostics, environmental Chemical Analysis, and food quality analysis. Paper- and thread-based devices are gaining their popularity in microfluidic or flow system since (1) these low cost and available cellulose-based materials, (2) compatible with biochemical and medical chemicals, and (3) liquid transportable via capillary force with no external force required. In paper-based device, microfluidic channels are created with different patterns so liquid can flow only in the given channel. In other word, the flow of liquid in microfluidic devices can be controlled. Research concerning paper-based microfluidic device is gaining its’ popularity. The most of published research focuses on (1) fabrication of low-cost paper-based microfluidic device with simple technique, and (2) applications of paper-based microfluidic device coupled with new detection methods such as analysis of images captured by smartphones using efficient and rapid color processing software. In this article, both fabrication techniques and various experiments of paper- and thread-based microfluidic devices concerning their detection efficiency and applications in classrooms published in periodic journals since 2007 are reviewed. In addition, strengths and weaknesses of the reviewed articles are discussed.
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References
Agustini, D., Bergamini, M. F., and Marcolino-Junior, L. H. (2018). Simple and inexpensive microfluidic thread based device for teaching microflow injection analysis and electrochemistry. Journal of Chemical Education, 95(8), 1411-1414.
Bruzewicz, D. A., Reches, M., & Whitesides, G. M. (2008). Low-cost printing of poly (dimethylsiloxane) barriers to define microchannels in paper. Analytical chemistry, 80(9), 3387-3392.
Cai, L., Wu, Y., Xu, C., and Chen, Z. (2012). A simple paper-based microfluidic device for the determination of the total amino acid content in a tea leaf extract. Journal of Chemical Education, 90(2), 232-234.
Cai, L., Zhang, X., Luo, L., Lin, H., Chen, J., Xu, C., Zhong, M., and Liao, X. (2019). Visual quantification of Fe on cotton thread using a ruler. Journal of Chemical Education, 96(7), 1532-1535.
Chatmontree, A., Chairam, S., Supasorn, S., Amatatongchai, M., Jarujamrus, P., Tamuang, S., and Somsook, E. (2015). Student fabrication and use of simple, low-cost, paper-based galvanic cells to investigate electrochemistry. Journal of Chemical Education, 92(6), 1044-1048.
ImageJ software. (2021) https://imagej.nih.gov/ij/ (accessed Nov. 2021).
Kajornklin, P., Jarujamrus, P., Phanphon, P., Ngernpradab, P., Supasorn, S., Chairam, S., Amatatongchai, M. (2020). Fabricating a low-cost, simple, screen-printed paper towel-based experimental device to demonstrate the factors affecting chemical equilibrium and chemical equilibrium constant, Kc. Journal of Chemical Education, 97(7), 1984–1991.
Lai, H., Li, Z., Zhu, S., Cai, L., Xu, C., and Zhou, Q. (2020). Naked-Eye detection of aluminum in gastric drugs on a paper-based analytical device. Journal of Chemical Education, 97(1), 295−299.
Mahadeva, S. K., Walus, K., and Stoeber, B. (2015). Paper as a platform for sensing applications and other devices: a review. ACS Applied Materials and Interfaces , 7(16), 8345-8362.
Martinez, A. W., Phillips, S. T., Butte, M. J., and Whitesides, G. M. (2007). Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angewandte Chemie International Edition, 46(8), 1318-20.
Namwong, P., Jarujamrus, P., Amatatongchai, M., and Chairam, S. (2018). Fabricating simple wax screen-printing paper-based analytical devices to demonstrate the concept of limiting reagent in acid–base reactions. Journal of Chemical Education, 95(2), 305-309.
Naksen, P, Saisui, P., Chomphu, T., Chaksuma, W., Anutrasakda, W. and Jarujamrus, P. (2021). Barcode-like paper sensor for water hardness detection. Journal of Science and Science Education, 4(1), 51-61.
Nilghaz, A., Liu, X., Ma, L., Huang, Q., and Lu, X. (2019). Development of fabric-based microfluidic devices by wax printing. Cellulose, 26(5), 3589-3599.
Prabpal, J., Vilaivan, T., and Praneenararat, T. (2017) Paper-based heavy metal sensors from the concise synthesis of an anionic porphyrin: a practical application of organic synthesis to environmental chemistry. Journal of Chemical Education, 94(8), 1137−1142.
Ravgiala, R. R., Weisburd, S., Sleeper, R., Martinez, A., Rozkiewicz, D., Whitesides, G. M., Hollar, K. A. (2014). Using Paper-based diagnostics with high school students to model forensic investigation and colorimetric analysis. Journal of Chemical Education, 91(1), 107-111.
Reches, M., Mirica, K. A., Dasgupta, R., Dickey. M. D., Butte, M. J. and Whitesides, G. M. (2010). Thread as a matrix for biomedical assays. ACS Applied Materials & Interfaces, 2, (6) 1722-1728.
Sameenoi, Y., Nongkai, P. N., Nouanthavong, S., Henry, C. S., and Nacapricha, D. (2014). One-step polymer screen-printing for microfluidic paper-based analytical device (PAD) fabrication. Analyst, 139(24), 6580-6588.
Xu, C., Cai, L., Zhong, M., and Zheng, S. (2015). Low-cost and rapid prototyping of microfluidic paper-based analytical devices by inkjet printing of permanent marker ink. RSC Advances, 5(7), 4770-4773.
Xu, C., Lin, W., Cai, L. (2016). Demonstrating electrophoretic separation in a straight paper channel delimited by a hydrophobic wax barrier. Journal of Chemical Education, 93(5), 903-905.
Xu, C., Jiang, D., Lin, J., and Cai, L. (2018). Cross channel thread-based microfluidic device for separation of food dyes. Journal of Chemical Education, 95(6), 1000-1003.
Zhang, Y., Zhou, C., Nie, J., Le, S., Qin, Q., Liu, F., Li, Y., and Li, J. (2014). Equipment-free quantitative measurement for microfluidic paper-based analytical devices fabricated using the principles of movable-type printing. Analytical chemistry, 86(4), 2005-2012.
Wang, B., Lin, Z., and Wang, M. (2015). Fabrication of a paper-based microfluidic device to readily determine nitrite ion concentration by simple colorimetric assay. Journal of Chemical Education, 92(4), 733-736.