Nutrition in cancer patients receiving chemotherapy

Authors

  • Pisamai Jangsuthivorawat Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University.
  • Naritsara Wongtong Panyananthaphikkhu Chonprathan Medical Center, Srinakharinwirot University.

Keywords:

Nutritional Status, Cancer Patients, Chemotherapy

Abstract

The purpose of this research is to assess the nutritional status. in cancer patients receiving chemotherapy. This research is a descriptive study. The population is cancer patients receiving chemotherapy at the chemotherapy nursing unit. Panyananthaphikkhu Medical Center using computational statistics, analysis of covariance (ANOVA), with the calculation value Estimate sample size for sample comparison of proportion to hypothesis value, obtained a sample size of 100 patients who were diagnosed with the disease. Cancer has been treated with chemotherapy, not combined with radiation. Age 15 years and over, including breast cancer. Colon cancer, lung cancer, cervical cancer, Endometrial cancer. The first time the disease was detected. Statistical data analysis using Mean, S.D., Percentage, Repeated measure ANOVA, and tools. Used to assess nutritional status using the Nutrition Alert Form (NAF score) adapted from the RAMA NAF score, Albumin level, and Total lymphocyte count. The results of the research found that the clinical data of 63 patients were collected because the research period had expired, and the sample was found not to be as specified. It was found that many patients were female, 47 cases (74.46%), males 16 cases (25.40%), average age 54.25 ± 13.5 years, average body mass index 22.93 ± 5.0 kg/m2, with the top 3 comorbidities being Breast cancer was 12 cases (22.20%), followed by colon cancer 9 cases (14.30%) and ovarian cancer 7 cases (11.10%). Most of the patients had no co-morbidities (44 cases) (69.80%) and had 19 co-morbidities. cases (30.20%) The most common diseases are High blood pressure, 11 cases (63.20%), followed by hyperlipidemia, 6 cases (31.60%), and diabetes, 4 cases (21.10), respectively. Nutrition Alert Form (NAF score) found that after giving chemotherapy Treatment at the 1st, 2nd and 3rd times found Mean ± S.D. = 4.77 ± 3.1, 4.89 ± 3.3 and 5.16 ± 2.9 (p-value = 0.173). Severity level Normal -Mild malnutrition Mean ± S.D. = 42 ± 66.7, 39 ± 61.9 and 37 ± 58.7 (p-value = 0.202). Albumin level after receiving chemotherapy in the 1st, 2nd and 3rd times Mean ± S.D. = 3.86 ± 0.6, 3.81 ± 0.5 and 3.71 ± 0.6 (p-value = 0.068). Albumin level ≤ 2.5 (g/l) was found Mean ± S.D. = 49 ± 77.0, 48 ± 76.0 and 42 ± 66.0 (p-value = 0.160). Total lymphocyte count found that after giving chemotherapy for the 1st, 2nd and 3rd times, the Mean (S.D.) values were found Mean ± S.D. = 2,128.85 ± 1263.7 1,897.85 ± 1058.9 and 1,756.57 ± 1219.0 (p-value = 0.028). TLC amount ≤ 1,000 cell/mm2 Mean ± S.D. = 44 ± 69.8, 38 ± 60.3 and 34 ± 54.0 (p-value = 0.003).

Downloads

Download data is not yet available.

References

อาคม เชียรศิลป์. (2560). ระบาดวิทยาของโรคมะเร็งในประเทศไทย. สืบค้นเมื่อ 25 กุมภาพันธ์ 2560, จาก http://www.oocities.org/suchartw/epidermiology

Rodgers III, G. M., Becker, P. S., Blinder, M., Cella, D., Chanan-Khan, A., Cleeland, C., Coccia, P. F., Djulbegovic, B., Gilreath, J. A., Kraut, E. H., Matulonis, U. A., Millenson, M. M., Reinke, D., Rosenthal, J., Schwartz, R. N., Soff, G., Stein, R. S., Vlahovic, G., and Weir III, A. B. (2012). Cancer- and chemotherapy-induced anemia: Clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network, 10(5), 628-653.

Kadokura, G., and Katsumata, N. (2014). Treatment of chemotherapy-induced anemia. Japanese Journal of Cancer and Chemotherapy, 41(4), 416-420.

Sharma, R., Tobin, P., and Clarke, S. J. (2005). Management of chemotherapy-induced nausea, vomiting, oral mucositis, and diarrhoea. Lancet Oncol, 6(2), 93-102. https://doi.org/10.1016/S1470-2045(05)01735-3

Argilés, J. M. (2005). Cancer-associated malnutrition. European Journal of Oncology Nursing, 9(Suppl. 2), S39-S50. https://doi.org/10.1016/j.ejon.2005.09.006

พวงทอง ไกรพิบูลย์. (2552). กินอย่างไรเมื่อเป็นมะเร็ง. กรุงเทพ: ซีเอ็ดยูเคชั่น.

Tisdale, M. J. (2002). Cachexia in cancer patients. Nature Reviews Cancer, 2(11), 862-871. https://doi.org/10.1038/nrc927

Arends, J., Strasser, F., Gonella, S., Solheim, T. S., Madeddu, C., Ravasco, P., Buonaccorso, L., de van der Schueren, M. A. E., Baldwin, C., Chasen, M., and Ripamonti, C. I. (2021). Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines. ESMO Open, 6(3). Article 100092. https://doi.org/10.1016/j.esmoop.2021.100092

Berger, A. (1998). Cochrane injuries group albumin reviewers why albumin may not work. BMJ, 317, 235-240. https://doi.org/10.1136/bmj.317.7153.235

จินตนา สุวิทวัส. (2564). การพยาบาลผู้ป่วยโรคมะเร็งที่มีภาวะขาดสารอาหารและพลังงาน. วารสารโรงพยาบาลมหาสารคาม, 18(2), 13-19.

Ma, L., Poulin, P., Feldstain, A., and Chasen, M. R. (2013). The association between malnutrition and psychological distress in patients with advanced head-and-neck cancer. Current Oncology, 20(6), e554-e560. https://doi.org/10.3747/co.20.1651

Manikantan, K., Khode, S., Sayed, S. I., Roe, J., Nutting, C. M., Rhys-Evans, P., Harrington, K. J., Kazi, R. (2009). Dysphagia in head and neck cancer. Cancer Treatment Reviews, 35(8), 724-732. https://doi.org/10.1016/j.ctrv.2009.08.008

ยุทธ ไกยวรรณ์. (2553). หลักสถิติวิจัยและการใช้โปรแกรม SPSS. กรุงเทพฯ: สำนักพิมพ์แห่งจุฬาลงกรณ์มหาวิทยาลัย.

Cortina, J. M. (1993). What is coefficient alpha? an examination of theory and applications. Journal of Applied Psychology, 78, 98-104. https://doi.org/10.1037/0021-9010.78.1.98

Downloads

Published

2025-06-13

How to Cite

Jangsuthivorawat, P., & Wongtong, N. (2025). Nutrition in cancer patients receiving chemotherapy. Srinakharinwirot Research and Development Journal of Humanities and Social Sciences, 17(1, January-June), 1–10, Article 269396. retrieved from https://so04.tci-thaijo.org/index.php/swurd/article/view/269396